Influences of Dopamine D2, D3 Agonist Quinpirole Dosage on Locomotor Activity Measured by Open-Field Test
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منابع مشابه
Effects of salvinorin A on locomotor sensitization to D2/D3 dopamine agonist quinpirole.
Locomotor sensitization induced by the dopamine agonist quinpirole can be potentiated by co-treatment with the synthetic kappa opioid agonist U69593. The identification of salvinorin A, an active component of the psychotropic sage Salvia divinorum, as a structurally different agonist of kappa-opioid receptors raised the question of whether this compound would similarly potentiate sensitization ...
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In Experiment 1, rats were trained to discriminate discrete sound sequences that varied in time or number. On time trials, the number of sounds was held constant at 4 and the duration of the sound sequence was either 2 or 8 s. On number trials, the duration of the sound sequence was held constant at 4 s, and the number of sounds was either 2 or 8. Psychophysical functions for time and number we...
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In this study, the ligand-receptor-G protein interactions of the dopamine D3 receptor expressed in Chinese hamster ovary cells were investigated using guanosine 5'-[gamma-thio]triphosphate-[35S] ([35S]GTPgammaS) and receptor binding experiments. Dopamine stimulated the [35S]GTPgammaS binding in a guanine nucleotide, magnesium and sodium-dependent manner. Dopamine and quinpirole produced maximal...
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Background: Ascorbic acid (AA) as a vitamin and neuromodulator is present in the most part of CNS such as nucleus accumbens shell (Acbsh), so the main purpose of this investigation was to evaluated the effect of AA and their Co-administration in Acbsh on anxiety and motor activity of rat by Open Field Test(OFT). Methods: Forty nine adult male Wistar rats (220-270 g) were used into 7 grou...
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ژورنال
عنوان ژورنال: ?? ???
سال: 2022
ISSN: ['2251-7189', '2251-8274']
DOI: https://doi.org/10.35986/me.2022.20.3.59